Enables RNA binding activity. Involved in protein localization to pericentriolar material. Located in Golgi apparatus and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for GOLGB1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = GOLGB1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of GOLGB1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr3:121,545,326–121,546,305 | 203.8 kb | Distal (>10kb) Multiome | 673 | |
| chr3:121,593,261–121,593,964 | 156.2 kb | Distal (>10kb) Multiome | 230 | |
| chr3:121,746,689–121,746,902 | 2.8 kb | Proximal (<10kb) | 35 | |
| chr3:121,749,162–121,750,214 | 65 bp | At TSS Multiome | 874 | |
| chr3:121,750,352–121,750,538 | 606 bp | At TSS | 56 | |
| chr3:121,834,395–121,835,766 | 85.4 kb | Distal (>10kb) Multiome | 839 | |
| chr3:121,894,283–121,894,849 | 144.8 kb | Distal (>10kb) Multiome | 105 | |
| chr3:122,021,702–122,022,458 | 272.4 kb | Distal (>10kb) Multiome | 376 |
Genomic view of the GOLGB1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.