Predicted to be involved in Golgi organization. Located in Golgi apparatus and cytosol. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for GOLGA8B. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = GOLGA8B upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of GOLGA8B, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr15:34,337,012–34,338,557 | 245.7 kb | Distal (>10kb) Multiome | 710 | |
| chr15:34,342,481–34,343,584 | 240.5 kb | Distal (>10kb) Multiome | 845 | |
| chr15:34,366,166–34,368,049 | 217.3 kb | Distal (>10kb) Multiome | 922 | |
| chr15:34,436,551–34,437,460 | 146.7 kb | Distal (>10kb) Multiome | 165 | |
| chr15:34,494,295–34,495,393 | 88.9 kb | Distal (>10kb) Multiome | 115 | |
| chr15:34,514,176–34,515,283 | 68.7 kb | Distal (>10kb) Multiome | 588 | |
| chr15:34,582,613–34,584,384 | 111 bp | At TSS Multiome | 711 | |
| chr15:34,588,076–34,588,619 | 5.2 kb | Proximal (<10kb) | 265 | |
| chr15:34,721,776–34,722,400 | 138.4 kb | Distal (>10kb) Multiome | 275 | |
| chr15:34,754,688–34,755,339 | 171.4 kb | Distal (>10kb) Multiome | 165 | |
| chr15:34,795,012–34,796,020 | 211.8 kb | Distal (>10kb) Multiome | 219 |
Genomic view of the GOLGA8B locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.