Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for FSD1L. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = FSD1L upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of FSD1L, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr9:104,778,305–104,779,370 | 669.1 kb | Distal (>10kb) Multiome HiCAR | 109 | |
| chr9:104,868,780–104,869,418 | 578.9 kb | Distal (>10kb) Multiome HiCAR | 308 | |
| chr9:105,244,049–105,245,808 | 202.8 kb | Distal (>10kb) Multiome | 1131 | |
| chr9:105,302,583–105,303,463 | 145.1 kb | Distal (>10kb) Multiome | 70 | |
| chr9:105,437,440–105,438,417 | 9.6 kb | Proximal (<10kb) | 84 | |
| chr9:105,447,454–105,448,988 | 3 bp | At TSS Multiome | 800 | |
| chr9:105,458,358–105,459,172 | 10.6 kb | Distal (>10kb) Multiome | 80 | |
| chr9:105,557,588–105,558,590 | 110.1 kb | Distal (>10kb) Multiome | 720 | |
| chr9:105,658,116–105,659,025 | 210.6 kb | Distal (>10kb) Multiome | 133 | |
| chr9:105,676,211–105,677,128 | 228.6 kb | Distal (>10kb) Multiome | 227 | |
| chr9:105,693,575–105,695,483 | 246.6 kb | Distal (>10kb) Multiome | 751 |
Genomic view of the FSD1L locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.