TFs regulating ENSG00000290929 0 TFs

Transcription factors with Perturb-seq knockdown data for ENSG00000290929. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ENSG00000290929 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to ENSG00000290929

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ENSG00000290929, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr2:207,831,341–207,832,383	280.7 kb	Distal (>10kb) Multiome	217
chr2:207,847,828–207,848,521	264.6 kb	Distal (>10kb) Multiome	603
chr2:207,905,345–207,906,166	206.9 kb	Distal (>10kb) Multiome	83
chr2:207,970,009–207,971,155	142.1 kb	Distal (>10kb) Multiome	256
chr2:208,025,250–208,025,873	87.1 kb	Distal (>10kb) Multiome	1046
chr2:208,112,378–208,113,769	537 bp	At TSS Multiome	285
chr2:208,124,049–208,124,760	11.7 kb	Distal (>10kb) Multiome	140
chr2:208,142,720–208,143,849	30.7 kb	Distal (>10kb) Multiome	333
chr2:208,215,744–208,216,551	103.5 kb	Distal (>10kb) Multiome	25
chr2:208,253,738–208,255,989	141.6 kb	Distal (>10kb) Multiome HiCAR	1085
chr2:208,265,281–208,266,835	153.6 kb	Distal (>10kb) Multiome	1005
chr2:208,267,505–208,268,088	155.2 kb	Distal (>10kb) Multiome	169
chr2:208,317,884–208,318,936	205.7 kb	Distal (>10kb) Multiome	106
chr2:208,406,386–208,407,453	294.3 kb	Distal (>10kb) Multiome	324

Genome Browser

Genomic view of the ENSG00000290929 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.