Enables RNA binding activity. Predicted to be involved in rRNA processing and ribosomal large subunit biogenesis. Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for EBNA1BP2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = EBNA1BP2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of EBNA1BP2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr1:42,923,882–42,925,144 | 247.8 kb | Distal (>10kb) Multiome | 878 | |
| chr1:42,957,739–42,959,536 | 213.3 kb | Distal (>10kb) Multiome | 943 | |
| chr1:43,007,293–43,009,203 | 163.5 kb | Distal (>10kb) Multiome | 496 | |
| chr1:43,147,490–43,148,180 | 24.5 kb | Distal (>10kb) Multiome | 318 | |
| chr1:43,172,043–43,172,806 | 232 bp | At TSS Multiome | 767 | |
| chr1:43,270,344–43,271,458 | 98.5 kb | Distal (>10kb) Multiome | 301 | |
| chr1:43,285,284–43,285,996 | 113.4 kb | Distal (>10kb) Multiome | 403 | |
| chr1:43,348,408–43,350,097 | 177.0 kb | Distal (>10kb) Multiome | 819 | |
| chr1:43,358,112–43,359,560 | 186.5 kb | Distal (>10kb) Multiome | 818 | |
| chr1:43,366,277–43,366,800 | 194.2 kb | Distal (>10kb) Multiome | 226 | |
| chr1:43,366,988–43,368,619 | 195.9 kb | Distal (>10kb) Multiome | 991 | |
| chr1:43,389,284–43,390,213 | 217.5 kb | Distal (>10kb) Multiome | 905 | |
| chr1:43,452,851–43,454,257 | 281.1 kb | Distal (>10kb) Multiome | 455 | |
| chr1:43,454,433–43,454,997 | 282.4 kb | Distal (>10kb) Multiome | 267 |
Genomic view of the EBNA1BP2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.