This module contains 57 genes including DANCR, SRY, VAMP2, NHERF2, and RBM4, enriched for male sex determination and membrane trafficking processes. Knockdown of ZC3H3, SOX17, GATAD2A, FOXH1, and ZNF532 activates this module. Knockdown of ZNF628, SOX11, and CTBP1 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.