DAGLB
diacylglycerol lipase beta | DAGLBETA, KCCR13L
DAGLB — as a Regulated Gene

TFs regulating DAGLB 0 TFs

Transcription factors with Perturb-seq knockdown data for DAGLB. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = DAGLB upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

Data: Effect:
TF Mean coef Binding Outlier TF→Gene link

Elements linked to DAGLB

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of DAGLB, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Accessibility Element Dist. to TSS Link type TFs
chr7:6,271,933–6,273,059 211.5 kb Distal (>10kb) Multiome 582
chr7:6,348,284–6,349,527 135.2 kb Distal (>10kb) Multiome 787
chr7:6,374,107–6,375,074 109.8 kb Distal (>10kb) Multiome 778
chr7:6,447,046–6,448,661 36.2 kb Distal (>10kb) Multiome 944
chr7:6,483,337–6,484,560 23 bp At TSS Multiome 748
chr7:6,502,814–6,505,187 19.9 kb Distal (>10kb) Multiome 573
chr7:6,516,399–6,516,954 32.4 kb Distal (>10kb) Multiome 245
chr7:6,526,260–6,527,132 42.5 kb Distal (>10kb) Multiome 313
chr7:6,530,620–6,531,774 47.0 kb Distal (>10kb) Multiome 296
chr7:6,536,237–6,537,265 52.7 kb Distal (>10kb) Multiome 223
chr7:6,577,282–6,577,787 93.3 kb Distal (>10kb) Multiome 840
chr7:6,589,551–6,590,781 105.8 kb Distal (>10kb) Multiome 802
chr7:6,614,875–6,616,376 131.3 kb Distal (>10kb) Multiome 610
chr7:6,640,237–6,641,084 156.4 kb Distal (>10kb) Multiome 238
chr7:6,663,809–6,664,686 179.9 kb Distal (>10kb) Multiome 232
chr7:6,706,296–6,707,347 222.8 kb Distal (>10kb) Multiome 718
chr7:6,729,225–6,730,453 245.5 kb Distal (>10kb) Multiome 755

Genome Browser

Genomic view of the DAGLB locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.

chr7:6,261,933 – 6,740,453
Proximal 1 kb Distal 10 kb Multiome HiCAR ATAC-seq RNA-seq