Predicted to enable microtubule plus-end binding activity. Predicted to be involved in cytoplasmic microtubule organization. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2025]
Transcription factors with Perturb-seq knockdown data for CLIP4. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CLIP4 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CLIP4, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr2:28,869,665–28,870,899 | 245.0 kb | Distal (>10kb) Multiome | 1009 | |
| chr2:28,894,052–28,895,454 | 220.8 kb | Distal (>10kb) Multiome | 992 | |
| chr2:29,052,737–29,054,280 | 61.9 kb | Distal (>10kb) Multiome | 269 | |
| chr2:29,055,442–29,056,614 | 59.5 kb | Distal (>10kb) Multiome | 136 | |
| chr2:29,114,952–29,116,267 | 2 bp | At TSS Multiome | 351 | |
| chr2:29,202,740–29,203,329 | 87.8 kb | Distal (>10kb) Multiome | 61 | |
| chr2:29,290,375–29,290,997 | 175.4 kb | Distal (>10kb) Multiome | 117 |
Genomic view of the CLIP4 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.