Enables identical protein binding activity. Predicted to be involved in innate immune response and regulation of defense response to virus. Located in centriole; centrosome; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CCDC92. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CCDC92 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CCDC92, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr12:123,711,684–123,712,955 | 260.6 kb | Distal (>10kb) Multiome | 771 | |
| chr12:123,719,176–123,720,140 | 253.2 kb | Distal (>10kb) Multiome | 303 | |
| chr12:123,761,832–123,763,058 | 210.8 kb | Distal (>10kb) Multiome | 416 | |
| chr12:123,971,679–123,974,128 | 157 bp | At TSS Multiome | 756 | |
| chr12:123,995,003–123,996,059 | 22.6 kb | Distal (>10kb) Multiome | 68 | |
| chr12:124,130,469–124,131,898 | 158.1 kb | Distal (>10kb) Multiome | 640 |
Genomic view of the CCDC92 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.