Enables RNA binding activity. Predicted to be involved in transcription by RNA polymerase II. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CCDC124. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CCDC124 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CCDC124, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr19:17,686,280–17,688,656 | 246.2 kb | Distal (>10kb) Multiome | 586 | |
| chr19:17,719,144–17,719,957 | 213.6 kb | Distal (>10kb) Multiome | 585 | |
| chr19:17,747,227–17,748,170 | 185.4 kb | Distal (>10kb) Multiome | 503 | |
| chr19:17,762,487–17,762,985 | 170.3 kb | Distal (>10kb) Multiome | 199 | |
| chr19:17,778,112–17,778,869 | 154.6 kb | Distal (>10kb) Multiome | 311 | |
| chr19:17,794,880–17,795,385 | 137.9 kb | Distal (>10kb) Multiome | 465 | |
| chr19:17,829,926–17,831,824 | 102.1 kb | Distal (>10kb) Multiome | 466 | |
| chr19:17,841,205–17,843,221 | 90.9 kb | Distal (>10kb) Multiome | 545 | |
| chr19:17,847,546–17,848,187 | 85.3 kb | Distal (>10kb) Multiome | 437 | |
| chr19:17,859,472–17,860,202 | 73.3 kb | Distal (>10kb) Multiome HiCAR | 822 | |
| chr19:17,873,769–17,874,763 | 58.8 kb | Distal (>10kb) Multiome HiCAR | 303 | |
| chr19:17,931,700–17,932,248 | 1.1 kb | Proximal (<10kb) Multiome | 136 | |
| chr19:17,932,373–17,933,607 | 221 bp | At TSS Multiome | 924 | |
| chr19:17,938,338–17,938,539 | 5.3 kb | Proximal (<10kb) | 264 | |
| chr19:17,942,639–17,943,673 | 10.3 kb | Distal (>10kb) Multiome | 302 | |
| chr19:17,947,203–17,950,613 | 15.0 kb | Distal (>10kb) Multiome | 639 | |
| chr19:17,951,201–17,952,652 | 19.2 kb | Distal (>10kb) Multiome | 237 | |
| chr19:17,966,756–17,967,353 | 34.1 kb | Distal (>10kb) Multiome | 127 | |
| chr19:18,000,754–18,001,614 | 68.1 kb | Distal (>10kb) Multiome | 788 | |
| chr19:18,007,024–18,008,451 | 75.1 kb | Distal (>10kb) Multiome | 681 | |
| chr19:18,058,070–18,058,878 | 125.5 kb | Distal (>10kb) Multiome | 542 | |
| chr19:18,104,219–18,104,847 | 171.5 kb | Distal (>10kb) Multiome | 466 | |
| chr19:18,109,636–18,110,594 | 177.1 kb | Distal (>10kb) Multiome | 601 | |
| chr19:18,117,556–18,118,528 | 184.9 kb | Distal (>10kb) Multiome | 550 | |
| chr19:18,152,230–18,153,823 | 219.8 kb | Distal (>10kb) Multiome | 809 | |
| chr19:18,160,950–18,161,791 | 228.4 kb | Distal (>10kb) Multiome | 494 | |
| chr19:18,173,513–18,174,441 | 240.8 kb | Distal (>10kb) Multiome | 667 | |
| chr19:18,192,530–18,193,908 | 260.0 kb | Distal (>10kb) Multiome | 758 | |
| chr19:18,202,796–18,205,452 | 271.2 kb | Distal (>10kb) Multiome | 823 | |
| chr19:18,220,660–18,221,487 | 288.0 kb | Distal (>10kb) Multiome | 134 | |
| chr19:18,223,665–18,226,306 | 291.0 kb | Distal (>10kb) Multiome | 790 | |
| chr19:18,232,737–18,233,413 | 300.1 kb | Distal (>10kb) Multiome | 789 |
Genomic view of the CCDC124 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.