Involved in DNA damage response and replication fork processing. Located in nucleoplasm. Part of Set1C/COMPASS complex. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for BOD1L1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = BOD1L1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of BOD1L1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr4:13,445,640–13,446,865 | 181.6 kb | Distal (>10kb) Multiome | 131 | |
| chr4:13,483,568–13,485,391 | 143.2 kb | Distal (>10kb) Multiome | 750 | |
| chr4:13,522,245–13,523,548 | 104.9 kb | Distal (>10kb) Multiome | 190 | |
| chr4:13,530,965–13,531,852 | 96.3 kb | Distal (>10kb) Multiome | 173 | |
| chr4:13,540,992–13,542,953 | 85.6 kb | Distal (>10kb) Multiome | 321 | |
| chr4:13,543,269–13,545,468 | 82.7 kb | Distal (>10kb) Multiome | 614 | |
| chr4:13,618,272–13,619,094 | 8.6 kb | Proximal (<10kb) | 151 | |
| chr4:13,627,080–13,628,352 | 67 bp | At TSS Multiome | 934 | |
| chr4:13,654,156–13,655,134 | 26.8 kb | Distal (>10kb) Multiome | 499 | |
| chr4:14,867,382–14,868,405 | 1240.2 kb | Distal (>10kb) Multiome HiCAR | 267 |
Genomic view of the BOD1L1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.