Enables RNA polymerase II complex binding activity. Involved in regulation of DNA-templated transcription elongation and regulation of RNA splicing. Located in nucleoplasm. Part of DBIRD complex. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZNF326. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF326 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF326, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr1:89,762,558–89,763,791 | 232.0 kb | Distal (>10kb) Multiome | 638 | |
| chr1:89,820,446–89,822,391 | 174.2 kb | Distal (>10kb) Multiome HiCAR | 889 | |
| chr1:89,842,655–89,844,211 | 151.6 kb | Distal (>10kb) Multiome HiCAR | 610 | |
| chr1:89,910,443–89,911,186 | 84.2 kb | Distal (>10kb) Multiome | 247 | |
| chr1:89,987,277–89,987,500 | 7.6 kb | Proximal (<10kb) | 215 | |
| chr1:89,994,463–89,995,789 | 26 bp | At TSS Multiome | 1039 | |
| chr1:89,995,975–89,996,297 | 842 bp | At TSS | 96 | |
| chr1:90,198,345–90,199,630 | 203.7 kb | Distal (>10kb) Multiome | 238 |
Genomic view of the ZNF326 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.