Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in chromosome; nuclear body; and nucleolus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZNF202. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF202 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF202, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr11:123,509,594–123,510,296 | 231.8 kb | Distal (>10kb) Multiome | 137 | |
| chr11:123,580,414–123,581,089 | 160.8 kb | Distal (>10kb) Multiome | 383 | |
| chr11:123,640,646–123,641,369 | 100.5 kb | Distal (>10kb) Multiome | 228 | |
| chr11:123,653,549–123,655,224 | 86.9 kb | Distal (>10kb) Multiome | 617 | |
| chr11:123,740,865–123,741,879 | 78 bp | At TSS Multiome | 789 | |
| chr11:123,741,997–123,743,161 | 1.1 kb | Proximal (<10kb) Multiome | 370 | |
| chr11:123,745,854–123,746,320 | 4.2 kb | Proximal (<10kb) | 57 | |
| chr11:123,775,088–123,776,113 | 33.9 kb | Distal (>10kb) Multiome | 148 | |
| chr11:123,796,181–123,796,630 | 54.9 kb | Distal (>10kb) Multiome | 36 | |
| chr11:123,865,333–123,866,263 | 124.0 kb | Distal (>10kb) Multiome | 63 | |
| chr11:123,876,205–123,876,809 | 134.9 kb | Distal (>10kb) Multiome | 11 | |
| chr11:124,068,701–124,070,224 | 327.3 kb | Distal (>10kb) Multiome HiCAR | 408 |
Genomic view of the ZNF202 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.