Predicted to enable protein-cysteine S-palmitoyltransferase activity. Involved in protein localization to plasma membrane and protein palmitoylation. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZDHHC23. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZDHHC23 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZDHHC23, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr3:113,695,756–113,697,740 | 251.2 kb | Distal (>10kb) Multiome | 796 | |
| chr3:113,744,989–113,747,921 | 201.0 kb | Distal (>10kb) Multiome | 1061 | |
| chr3:113,838,330–113,839,358 | 109.1 kb | Distal (>10kb) Multiome | 588 | |
| chr3:113,947,254–113,948,963 | 169 bp | At TSS Multiome | 685 | |
| chr3:114,056,072–114,057,305 | 108.7 kb | Distal (>10kb) Multiome | 831 | |
| chr3:114,152,492–114,153,196 | 204.9 kb | Distal (>10kb) Multiome | 653 | |
| chr3:114,153,953–114,154,968 | 206.7 kb | Distal (>10kb) Multiome | 184 | |
| chr3:114,213,304–114,215,564 | 266.8 kb | Distal (>10kb) Multiome | 461 |
Genomic view of the ZDHHC23 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.