Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in Golgi apparatus and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for YIF1A. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = YIF1A upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of YIF1A, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr11:66,001,882–66,002,962 | 286.7 kb | Distal (>10kb) Multiome | 1022 | |
| chr11:66,007,227–66,007,703 | 281.6 kb | Distal (>10kb) Multiome | 100 | |
| chr11:66,022,341–66,022,903 | 266.5 kb | Distal (>10kb) Multiome | 466 | |
| chr11:66,045,170–66,045,637 | 243.8 kb | Distal (>10kb) Multiome | 394 | |
| chr11:66,048,912–66,049,460 | 240.0 kb | Distal (>10kb) Multiome | 83 | |
| chr11:66,051,716–66,052,760 | 236.9 kb | Distal (>10kb) Multiome | 901 | |
| chr11:66,069,690–66,071,102 | 219.0 kb | Distal (>10kb) Multiome | 622 | |
| chr11:66,256,991–66,258,893 | 31.2 kb | Distal (>10kb) Multiome | 844 | |
| chr11:66,266,650–66,269,501 | 21.6 kb | Distal (>10kb) Multiome | 869 | |
| chr11:66,277,646–66,278,447 | 11.0 kb | Distal (>10kb) Multiome | 363 | |
| chr11:66,282,288–66,283,017 | 6.5 kb | Proximal (<10kb) Multiome | 618 | |
| chr11:66,288,772–66,289,992 | 219 bp | At TSS Multiome | 944 | |
| chr11:66,291,733–66,292,085 | 2.6 kb | Proximal (<10kb) | 122 | |
| chr11:66,311,658–66,313,958 | 23.0 kb | Distal (>10kb) Multiome | 1005 | |
| chr11:66,316,861–66,317,347 | 27.9 kb | Distal (>10kb) Multiome | 164 | |
| chr11:66,328,223–66,328,781 | 39.4 kb | Distal (>10kb) Multiome | 662 | |
| chr11:66,344,804–66,345,488 | 56.0 kb | Distal (>10kb) Multiome | 731 | |
| chr11:66,347,078–66,348,463 | 58.7 kb | Distal (>10kb) Multiome | 866 | |
| chr11:66,370,733–66,372,576 | 82.7 kb | Distal (>10kb) Multiome | 800 | |
| chr11:66,408,467–66,409,206 | 119.6 kb | Distal (>10kb) Multiome | 569 | |
| chr11:66,421,258–66,422,129 | 132.6 kb | Distal (>10kb) Multiome | 1190 | |
| chr11:66,438,544–66,439,241 | 149.8 kb | Distal (>10kb) Multiome | 756 | |
| chr11:66,466,155–66,467,634 | 177.7 kb | Distal (>10kb) Multiome | 579 | |
| chr11:66,479,578–66,480,947 | 191.2 kb | Distal (>10kb) Multiome | 937 | |
| chr11:66,510,277–66,510,954 | 221.5 kb | Distal (>10kb) Multiome | 787 | |
| chr11:66,545,631–66,547,072 | 257.0 kb | Distal (>10kb) Multiome | 753 | |
| chr11:66,568,061–66,568,910 | 279.4 kb | Distal (>10kb) Multiome | 392 |
Genomic view of the YIF1A locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.