Enables UDP-glycosyltransferase activity. Acts upstream of or within cellular response to genistein. Predicted to be located in membrane. Predicted to be part of UDP-N-acetylglucosamine transferase complex. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for UGT3A2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = UGT3A2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of UGT3A2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr5:35,990,527–35,991,889 | 75.5 kb | Distal (>10kb) Multiome | 224 | |
| chr5:36,058,608–36,059,208 | 7.7 kb | Proximal (<10kb) | 42 | |
| chr5:36,059,500–36,059,945 | 6.9 kb | Proximal (<10kb) | 24 | |
| chr5:36,066,087–36,067,458 | 4 bp | At TSS Multiome | 263 | |
| chr5:36,073,626–36,074,139 | 6.7 kb | Proximal (<10kb) | 164 | |
| chr5:36,079,210–36,079,750 | 12.6 kb | Distal (>10kb) Multiome | 279 | |
| chr5:36,089,810–36,090,388 | 23.3 kb | Distal (>10kb) Multiome | 138 | |
| chr5:36,151,057–36,152,602 | 85.1 kb | Distal (>10kb) Multiome | 883 | |
| chr5:36,240,767–36,242,724 | 175.3 kb | Distal (>10kb) Multiome | 1133 | |
| chr5:36,689,905–36,690,922 | 623.6 kb | Distal (>10kb) Multiome HiCAR | 674 | |
| chr5:36,692,732–36,693,630 | 626.4 kb | Distal (>10kb) Multiome HiCAR | 332 | |
| chr5:36,701,409–36,702,282 | 634.9 kb | Distal (>10kb) Multiome HiCAR | 152 |
Genomic view of the UGT3A2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.