Predicted to be involved in chromatin organization. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for UBN2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = UBN2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of UBN2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr7:138,980,951–138,982,350 | 249.7 kb | Distal (>10kb) Multiome | 525 | |
| chr7:139,034,996–139,036,579 | 195.2 kb | Distal (>10kb) Multiome | 626 | |
| chr7:139,090,840–139,094,844 | 137.5 kb | Distal (>10kb) Multiome | 732 | |
| chr7:139,108,547–139,110,090 | 121.6 kb | Distal (>10kb) Multiome | 920 | |
| chr7:139,124,120–139,124,640 | 106.8 kb | Distal (>10kb) Multiome | 304 | |
| chr7:139,133,422–139,134,016 | 97.5 kb | Distal (>10kb) Multiome | 936 | |
| chr7:139,230,473–139,232,505 | 123 bp | At TSS Multiome | 971 | |
| chr7:139,339,925–139,342,077 | 109.2 kb | Distal (>10kb) Multiome | 1259 | |
| chr7:139,359,044–139,360,936 | 129.2 kb | Distal (>10kb) Multiome | 1134 | |
| chr7:139,482,716–139,484,133 | 252.5 kb | Distal (>10kb) Multiome | 464 | |
| chr7:139,499,861–139,500,450 | 268.9 kb | Distal (>10kb) Multiome | 482 | |
| chr7:139,523,378–139,524,503 | 292.6 kb | Distal (>10kb) Multiome | 136 |
Genomic view of the UBN2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.