Enables gamma-tubulin binding activity. Predicted to be involved in meiotic cell cycle; microtubule cytoskeleton organization; and mitotic cell cycle. Located in cytoplasm and microtubule cytoskeleton. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for TUBGCP3. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = TUBGCP3 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of TUBGCP3, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr13:111,067,321–111,068,017 | 1520.6 kb | Distal (>10kb) Multiome HiCAR | 435 | |
| chr13:112,443,518–112,444,440 | 144.0 kb | Distal (>10kb) Multiome | 229 | |
| chr13:112,587,337–112,588,413 | 80 bp | At TSS Multiome | 1083 | |
| chr13:112,606,168–112,606,859 | 18.4 kb | Distal (>10kb) Multiome | 517 | |
| chr13:112,689,000–112,690,944 | 101.9 kb | Distal (>10kb) Multiome | 778 | |
| chr13:112,711,516–112,712,479 | 123.8 kb | Distal (>10kb) Multiome | 761 | |
| chr13:112,885,816–112,886,312 | 297.9 kb | Distal (>10kb) Multiome | 440 |
Genomic view of the TUBGCP3 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.