Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; vesicle coating; and vesicle tethering. Predicted to be located in cytosol. Predicted to be part of TRAPPIII protein complex. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for TRAPPC13. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = TRAPPC13 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of TRAPPC13, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr5:65,481,460–65,482,620 | 143.1 kb | Distal (>10kb) Multiome | 583 | |
| chr5:65,562,647–65,563,667 | 61.8 kb | Distal (>10kb) Multiome | 818 | |
| chr5:65,623,893–65,625,295 | 473 bp | At TSS Multiome | 910 | |
| chr5:65,721,358–65,723,398 | 97.1 kb | Distal (>10kb) Multiome | 848 |
Genomic view of the TRAPPC13 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.