Enables RNA binding activity. Involved in spliceosomal snRNP assembly. Located in cytosol and nucleus. Part of several cellular components, including methylosome; nucleus; and pICln-Sm protein complex. Biomarker of nasopharynx carcinoma. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SNRPF. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SNRPF upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SNRPF, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr12:95,745,876–95,746,868 | 112.6 kb | Distal (>10kb) Multiome | 68 | |
| chr12:95,789,276–95,791,638 | 68.4 kb | Distal (>10kb) Multiome | 591 | |
| chr12:95,857,246–95,857,510 | 1.4 kb | Proximal (<10kb) | 33 | |
| chr12:95,858,308–95,859,272 | 71 bp | At TSS Multiome | 778 | |
| chr12:95,942,226–95,943,879 | 84.0 kb | Distal (>10kb) Multiome | 840 | |
| chr12:96,034,637–96,036,352 | 176.8 kb | Distal (>10kb) Multiome | 921 |
Genomic view of the SNRPF locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.