Predicted to be involved in RNA processing. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SNORA33. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SNORA33 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SNORA33, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr6:132,812,426–132,813,000 | 4.2 kb | Proximal (<10kb) | 230 | |
| chr6:132,813,124–132,815,456 | 1.8 kb | Proximal (<10kb) | 1156 | |
| chr6:132,818,204–132,820,198 | 985 bp | At TSS | 501 | |
| chr6:132,820,314–132,821,624 | 3.1 kb | Proximal (<10kb) | 402 | |
| chr6:132,821,743–132,823,420 | 4.5 kb | Proximal (<10kb) | 275 | |
| chr6:132,823,548–132,823,914 | 6.3 kb | Proximal (<10kb) | 35 | |
| chr6:132,824,017–132,825,052 | 6.8 kb | Proximal (<10kb) | 32 | |
| chr6:132,825,197–132,825,946 | 8.0 kb | Proximal (<10kb) | 11 |
Genomic view of the SNORA33 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.