Predicted to enable D-glucose:sodium symporter activity. Predicted to be involved in hexose transmembrane transport. Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SLC5A9. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SLC5A9 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SLC5A9, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr1:47,948,155–47,948,873 | 274.3 kb | Distal (>10kb) Multiome | 161 | |
| chr1:47,983,776–47,984,855 | 238.4 kb | Distal (>10kb) Multiome | 157 | |
| chr1:47,996,187–47,998,080 | 225.0 kb | Distal (>10kb) Multiome | 504 | |
| chr1:48,024,695–48,025,655 | 197.5 kb | Distal (>10kb) Multiome | 216 | |
| chr1:48,051,694–48,052,373 | 170.6 kb | Distal (>10kb) Multiome | 82 | |
| chr1:48,068,111–48,069,002 | 154.3 kb | Distal (>10kb) Multiome | 109 | |
| chr1:48,073,607–48,074,075 | 148.8 kb | Distal (>10kb) Multiome | 90 | |
| chr1:48,208,078–48,209,322 | 13.8 kb | Distal (>10kb) Multiome | 64 | |
| chr1:48,212,866–48,213,098 | 9.6 kb | Proximal (<10kb) | 5 | |
| chr1:48,214,255–48,215,241 | 8.1 kb | Proximal (<10kb) Multiome | 110 | |
| chr1:48,228,237–48,228,582 | 5.6 kb | Proximal (<10kb) | 64 | |
| chr1:48,236,700–48,237,325 | 2.1 kb | Proximal (<10kb) | 117 | |
| chr1:48,248,368–48,248,811 | 9.0 kb | Proximal (<10kb) | 13 | |
| chr1:48,442,425–48,443,673 | 220.4 kb | Distal (>10kb) Multiome | 216 | |
| chr1:48,471,474–48,472,912 | 249.5 kb | Distal (>10kb) Multiome | 545 | |
| chr1:48,498,158–48,499,133 | 275.8 kb | Distal (>10kb) Multiome HiCAR | 244 | |
| chr1:48,499,218–48,501,656 | 278.2 kb | Distal (>10kb) Multiome | 297 | |
| chr1:48,530,436–48,531,227 | 308.2 kb | Distal (>10kb) Multiome | 414 |
Genomic view of the SLC5A9 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.