Located in Golgi apparatus; plasma membrane; and synaptic vesicle membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SLC35G2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SLC35G2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SLC35G2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr3:136,751,181–136,753,220 | 66.5 kb | Distal (>10kb) Multiome | 1046 | |
| chr3:136,811,796–136,811,975 | 7.1 kb | Proximal (<10kb) | 26 | |
| chr3:136,818,266–136,818,496 | 586 bp | At TSS | 223 | |
| chr3:136,818,569–136,819,674 | 24 bp | At TSS Multiome | 656 | |
| chr3:136,819,787–136,820,421 | 1.2 kb | Proximal (<10kb) Multiome | 524 | |
| chr3:136,861,045–136,862,941 | 43.1 kb | Distal (>10kb) Multiome | 966 | |
| chr3:137,032,463–137,033,394 | 213.7 kb | Distal (>10kb) Multiome | 351 |
Genomic view of the SLC35G2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.