This gene encodes a transmembrane protein which is a member of the drug/metabolite transporter protein superfamily. The encoded protein may play a role in the regulation of calcium levels inside the cell. [provided by RefSeq, Sep 2016]
Transcription factors with Perturb-seq knockdown data for SLC35G1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SLC35G1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SLC35G1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr10:93,702,336–93,703,002 | 191.4 kb | Distal (>10kb) Multiome | 1036 | |
| chr10:93,748,844–93,749,704 | 144.7 kb | Distal (>10kb) Multiome | 214 | |
| chr10:93,841,872–93,842,361 | 51.9 kb | Distal (>10kb) Multiome | 102 | |
| chr10:93,893,623–93,894,609 | 3 bp | At TSS Multiome | 664 | |
| chr10:93,993,307–93,994,580 | 100.0 kb | Distal (>10kb) Multiome | 386 | |
| chr10:94,006,733–94,007,498 | 113.3 kb | Distal (>10kb) Multiome | 178 | |
| chr10:94,105,068–94,105,823 | 211.4 kb | Distal (>10kb) Multiome | 100 |
Genomic view of the SLC35G1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.