SLC2A4RG
SLC2A4 regulator | GEF, GLUT4EF, HDBP1, Si-1-2, Si-1-2-19

The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. The encoded protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene. [provided by RefSeq, Jul 2008]

Member of: DE-1 DE-1.21 Developmental clusters: GC6
Biological processes 9 terms
DNA-binding transcription factor activity (GO:0003700)DNA-binding transcription factor activity (GO:0003700)RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978)cytoplasm (GO:0005737)nucleus (GO:0005634)nucleus (GO:0005634)nucleus (GO:0005634)regulation of DNA-templated transcription (GO:0006355)regulation of transcription by RNA polymerase II (GO:0006357)
Expression (TPM)
SLC2A4RG — as a Regulated Gene

TFs regulating SLC2A4RG 0 TFs

Transcription factors with Perturb-seq knockdown data for SLC2A4RG. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SLC2A4RG upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

Data: Effect:
TF Mean coef Binding Outlier TF→Gene link

Elements linked to SLC2A4RG

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SLC2A4RG, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Accessibility Element Dist. to TSS Link type TFs
chr20:63,471,533–63,472,788 267.6 kb Distal (>10kb) Multiome 219
chr20:63,488,166–63,488,632 251.8 kb Distal (>10kb) Multiome 127
chr20:63,498,850–63,499,391 241.0 kb Distal (>10kb) Multiome 232
chr20:63,519,657–63,521,677 219.6 kb Distal (>10kb) Multiome 712
chr20:63,537,759–63,538,455 202.2 kb Distal (>10kb) Multiome 823
chr20:63,552,551–63,554,733 186.7 kb Distal (>10kb) Multiome 544
chr20:63,573,969–63,574,596 165.9 kb Distal (>10kb) Multiome 551
chr20:63,626,480–63,627,647 113.2 kb Distal (>10kb) Multiome 982
chr20:63,641,266–63,642,913 98.2 kb Distal (>10kb) Multiome 691
chr20:63,652,233–63,654,166 86.7 kb Distal (>10kb) Multiome 1011
chr20:63,657,813–63,658,939 81.8 kb Distal (>10kb) Multiome 1055
chr20:63,696,254–63,697,070 43.7 kb Distal (>10kb) Multiome 458
chr20:63,707,489–63,708,488 32.3 kb Distal (>10kb) Multiome 1008
chr20:63,737,573–63,741,470 580 bp At TSS Multiome 1098
chr20:63,775,216–63,775,997 35.2 kb Distal (>10kb) Multiome 257
chr20:63,830,341–63,832,721 91.1 kb Distal (>10kb) Multiome 628
chr20:63,846,273–63,846,790 106.2 kb Distal (>10kb) Multiome 487
chr20:63,864,234–63,865,991 124.9 kb Distal (>10kb) Multiome 1158
chr20:63,894,341–63,895,764 154.8 kb Distal (>10kb) Multiome 791
chr20:63,938,191–63,939,815 198.5 kb Distal (>10kb) Multiome 287
chr20:63,939,918–63,942,008 201.4 kb Distal (>10kb) Multiome 496
chr20:63,955,375–63,956,875 216.1 kb Distal (>10kb) Multiome 1107
chr20:63,956,976–63,958,127 217.4 kb Distal (>10kb) Multiome 709
chr20:63,969,149–63,970,667 229.7 kb Distal (>10kb) Multiome 764
chr20:63,973,660–63,974,150 233.7 kb Distal (>10kb) Multiome 767
chr20:63,980,541–63,981,488 240.9 kb Distal (>10kb) Multiome 986
chr20:64,030,226–64,031,221 290.5 kb Distal (>10kb) Multiome 159
chr20:64,038,338–64,039,469 298.9 kb Distal (>10kb) Multiome 628

Genome Browser

Genomic view of the SLC2A4RG locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.

chr20:63,461,533 – 64,049,469
Proximal 1 kb Distal 10 kb Multiome HiCAR ATAC-seq RNA-seq
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