SLC25A22
solute carrier family 25 member 22 | EIEE3, FLJ13044, GC-1, GC1, NET44
SLC25A22 — as a Regulated Gene

TFs regulating SLC25A22 0 TFs

Transcription factors with Perturb-seq knockdown data for SLC25A22. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SLC25A22 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

Data: Effect:
TF Mean coef Binding Outlier TF→Gene link

Elements linked to SLC25A22

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SLC25A22, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Accessibility Element Dist. to TSS Link type TFs
chr11:506,153–507,989 291.1 kb Distal (>10kb) Multiome 977
chr11:534,525–536,399 262.6 kb Distal (>10kb) Multiome 673
chr11:536,654–537,918 260.8 kb Distal (>10kb) Multiome 558
chr11:554,380–556,321 243.1 kb Distal (>10kb) Multiome 460
chr11:559,830–562,079 237.4 kb Distal (>10kb) Multiome 791
chr11:567,850–569,533 229.7 kb Distal (>10kb) Multiome 672
chr11:574,830–576,748 222.1 kb Distal (>10kb) Multiome 793
chr11:613,334–614,059 184.6 kb Distal (>10kb) Multiome 215
chr11:615,262–616,320 182.4 kb Distal (>10kb) Multiome 443
chr11:636,786–637,700 161.2 kb Distal (>10kb) Multiome 161
chr11:693,835–696,330 102.9 kb Distal (>10kb) Multiome 873
chr11:705,737–706,270 92.3 kb Distal (>10kb) Multiome 361
chr11:720,619–721,074 77.4 kb Distal (>10kb) Multiome 156
chr11:727,901–728,499 70.1 kb Distal (>10kb) Multiome 686
chr11:746,704–748,069 51.0 kb Distal (>10kb) Multiome 755
chr11:762,582–763,602 35.0 kb Distal (>10kb) Multiome 326
chr11:776,216–778,328 20.9 kb Distal (>10kb) Multiome 770
chr11:783,385–783,909 14.6 kb Distal (>10kb) Multiome 278
chr11:797,112–798,675 10 bp At TSS Multiome 697
chr11:804,241–805,812 7.0 kb Proximal (<10kb) Multiome 725
chr11:808,894–810,402 11.4 kb Distal (>10kb) Multiome 976
chr11:818,369–820,592 21.2 kb Distal (>10kb) Multiome 749
chr11:826,980–828,116 29.3 kb Distal (>10kb) Multiome 662
chr11:828,933–831,262 32.0 kb Distal (>10kb) Multiome 491
chr11:832,323–833,565 34.5 kb Distal (>10kb) Multiome 562
chr11:842,034–843,556 44.4 kb Distal (>10kb) Multiome 794
chr11:843,773–845,220 46.2 kb Distal (>10kb) Multiome 664
chr11:849,082–850,270 51.4 kb Distal (>10kb) Multiome 229
chr11:910,337–911,591 112.7 kb Distal (>10kb) Multiome 754
chr11:925,038–926,264 127.5 kb Distal (>10kb) Multiome 689

Genome Browser

Genomic view of the SLC25A22 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.

chr11:496,153 – 936,264
Proximal 1 kb Distal 10 kb Multiome HiCAR ATAC-seq RNA-seq