Enables carnitine transmembrane transporter activity and creatine transmembrane transporter activity. Involved in carnitine transmembrane transport; creatine transmembrane transport; and urate metabolic process. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SLC16A9. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SLC16A9 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SLC16A9, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr10:59,700,800–59,701,030 | 8.8 kb | Proximal (<10kb) | 29 | |
| chr10:59,708,672–59,710,741 | 60 bp | At TSS Multiome | 600 | |
| chr10:59,847,061–59,847,658 | 137.6 kb | Distal (>10kb) Multiome | 103 | |
| chr10:59,905,191–59,907,242 | 196.8 kb | Distal (>10kb) Multiome | 1011 | |
| chr10:59,907,971–59,908,967 | 198.7 kb | Distal (>10kb) Multiome | 483 | |
| chr10:60,003,360–60,004,346 | 294.0 kb | Distal (>10kb) Multiome | 154 |
Genomic view of the SLC16A9 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.