Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for SCGB2B2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SCGB2B2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SCGB2B2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr19:34,404,022–34,405,020 | 272.8 kb | Distal (>10kb) Multiome | 883 | |
| chr19:34,428,165–34,428,863 | 248.8 kb | Distal (>10kb) Multiome | 809 | |
| chr19:34,480,917–34,482,711 | 195.5 kb | Distal (>10kb) Multiome | 520 | |
| chr19:34,501,375–34,501,856 | 175.4 kb | Distal (>10kb) Multiome | 590 | |
| chr19:34,668,047–34,668,472 | 8.7 kb | Proximal (<10kb) Multiome | 24 | |
| chr19:34,676,923–34,678,053 | 467 bp | At TSS Multiome | 728 | |
| chr19:34,733,416–34,734,655 | 57.0 kb | Distal (>10kb) Multiome | 1008 | |
| chr19:34,772,709–34,773,413 | 96.0 kb | Distal (>10kb) Multiome | 680 | |
| chr19:34,920,040–34,921,057 | 243.4 kb | Distal (>10kb) Multiome | 309 | |
| chr19:34,926,731–34,927,343 | 249.8 kb | Distal (>10kb) Multiome | 741 | |
| chr19:34,963,909–34,964,414 | 287.0 kb | Distal (>10kb) Multiome | 645 |
Genomic view of the SCGB2B2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.