Predicted to enable phosphatidic acid transfer activity. Predicted to be involved in phospholipid transport. Predicted to be active in mitochondrial intermembrane space. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for PRELID2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = PRELID2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of PRELID2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr5:144,504,722–144,505,775 | 1330.1 kb | Distal (>10kb) Multiome HiCAR | 206 | |
| chr5:145,825,797–145,825,903 | 9.4 kb | Proximal (<10kb) | 130 | |
| chr5:145,834,746–145,836,489 | 75 bp | At TSS Multiome | 918 | |
| chr5:145,838,088–145,838,731 | 2.7 kb | Proximal (<10kb) | 101 | |
| chr5:145,855,918–145,856,897 | 21.2 kb | Distal (>10kb) Multiome | 434 | |
| chr5:145,936,249–145,937,190 | 101.3 kb | Distal (>10kb) Multiome | 653 | |
| chr5:146,026,278–146,026,799 | 191.1 kb | Distal (>10kb) Multiome | 138 | |
| chr5:146,073,032–146,074,223 | 238.3 kb | Distal (>10kb) Multiome | 179 |
Genomic view of the PRELID2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.