This gene encodes a protein with glycosyltransferase activity although its function is not currently known. [provided by RefSeq, Sep 2012]
Transcription factors with Perturb-seq knockdown data for POMGNT2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = POMGNT2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of POMGNT2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr3:42,805,298–42,806,226 | 300.1 kb | Distal (>10kb) Multiome | 381 | |
| chr3:42,880,478–42,881,506 | 224.9 kb | Distal (>10kb) Multiome | 685 | |
| chr3:42,884,409–42,884,926 | 221.5 kb | Distal (>10kb) Multiome | 59 | |
| chr3:42,979,048–42,979,795 | 126.6 kb | Distal (>10kb) Multiome | 351 | |
| chr3:43,105,389–43,106,477 | 25 bp | At TSS Multiome | 588 | |
| chr3:43,286,148–43,287,266 | 180.5 kb | Distal (>10kb) Multiome | 644 |
Genomic view of the POMGNT2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.