Enables RNA binding activity. Located in several cellular components, including cytoplasmic stress granule; nuclear body; and ribosome. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for NUFIP2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = NUFIP2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of NUFIP2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr17:29,005,841–29,006,414 | 288.1 kb | Distal (>10kb) Multiome | 707 | |
| chr17:29,039,928–29,040,500 | 253.9 kb | Distal (>10kb) Multiome | 99 | |
| chr17:29,042,531–29,043,259 | 251.3 kb | Distal (>10kb) Multiome | 553 | |
| chr17:29,148,688–29,149,641 | 145.2 kb | Distal (>10kb) Multiome HiCAR | 709 | |
| chr17:29,176,562–29,177,220 | 117.3 kb | Distal (>10kb) Multiome | 782 | |
| chr17:29,179,268–29,180,802 | 114.7 kb | Distal (>10kb) Multiome | 781 | |
| chr17:29,292,464–29,294,599 | 1.4 kb | Proximal (<10kb) Multiome | 1029 | |
| chr17:29,369,902–29,370,603 | 76.0 kb | Distal (>10kb) Multiome | 305 | |
| chr17:29,389,919–29,391,325 | 96.2 kb | Distal (>10kb) Multiome | 863 | |
| chr17:29,566,006–29,569,574 | 274.5 kb | Distal (>10kb) Multiome HiCAR | 868 | |
| chr17:29,572,746–29,573,303 | 278.8 kb | Distal (>10kb) Multiome | 252 | |
| chr17:29,588,688–29,590,312 | 295.5 kb | Distal (>10kb) Multiome | 590 | |
| chr17:29,590,975–29,592,562 | 297.6 kb | Distal (>10kb) Multiome | 810 |
Genomic view of the NUFIP2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.