MT-ND6

NADH dehydrogenase subunit 6 | NAD6, ND6, MTND6

Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Located in mitochondrial inner membrane. Implicated in Leber hereditary optic neuropathy; Leigh disease; and spinal muscular atrophy with lower extremity predominant 2B. [provided by Alliance of Genome Resources, Jul 2025]

Member of: DE-3 DE-3.2 Developmental clusters: GC2

Biological processes 17 terms

NADH dehydrogenase (ubiquinone) activity (GO:0008137)NADH dehydrogenase (ubiquinone) activity (GO:0008137)aerobic respiration (GO:0009060)mitochondrial electron transport, NADH to ubiquinone (GO:0006120)mitochondrial electron transport, NADH to ubiquinone (GO:0006120)mitochondrial inner membrane (GO:0005743)mitochondrial inner membrane (GO:0005743)mitochondrial inner membrane (GO:0005743)mitochondrial inner membrane (GO:0005743)mitochondrial inner membrane (GO:0005743)mitochondrial respiratory chain complex I assembly (GO:0032981)mitochondrial respiratory chain complex I assembly (GO:0032981)mitochondrion (GO:0005739)mitochondrion (GO:0005739)proton motive force-driven mitochondrial ATP synthesis (GO:0042776)proton transmembrane transport (GO:1902600)respiratory chain complex I (GO:0045271)

Expression (TPM)