Enables calcium ion binding activity. Predicted to be involved in regulation of neurotransmitter secretion. Located in cytosol; membrane; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for MCTP2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = MCTP2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of MCTP2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr15:93,029,697–93,031,417 | 1200.7 kb | Distal (>10kb) Multiome HiCAR | 387 | |
| chr15:94,126,833–94,127,772 | 104.3 kb | Distal (>10kb) Multiome | 42 | |
| chr15:94,228,743–94,228,945 | 2.6 kb | Proximal (<10kb) | 16 | |
| chr15:94,230,728–94,232,470 | 51 bp | At TSS Multiome | 567 | |
| chr15:94,234,134–94,234,252 | 2.6 kb | Proximal (<10kb) | 13 | |
| chr15:94,234,370–94,234,895 | 2.8 kb | Proximal (<10kb) | 80 | |
| chr15:94,237,689–94,237,874 | 6.1 kb | Proximal (<10kb) | 3 | |
| chr15:94,381,415–94,381,880 | 150.1 kb | Distal (>10kb) Multiome | 101 |
Genomic view of the MCTP2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.