Enables 14-3-3 protein binding activity and protein kinase binding activity. Involved in regulation of axonogenesis. Located in axon and cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for KIF13B. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = KIF13B upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of KIF13B, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr8:29,146,567–29,147,479 | 116.2 kb | Distal (>10kb) Multiome | 158 | |
| chr8:29,262,401–29,263,703 | 26 bp | At TSS Multiome | 641 | |
| chr8:29,318,868–29,320,832 | 56.6 kb | Distal (>10kb) Multiome | 261 | |
| chr8:29,347,713–29,349,581 | 85.5 kb | Distal (>10kb) Multiome | 441 | |
| chr8:29,349,763–29,351,657 | 87.7 kb | Distal (>10kb) Multiome | 719 | |
| chr8:29,408,273–29,408,752 | 145.4 kb | Distal (>10kb) Multiome | 166 | |
| chr8:29,432,484–29,433,492 | 169.7 kb | Distal (>10kb) Multiome | 83 | |
| chr8:29,529,634–29,530,152 | 266.8 kb | Distal (>10kb) Multiome | 382 |
Genomic view of the KIF13B locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.