Enables Notch binding activity and polypeptide N-acetylgalactosaminyltransferase activity. Involved in protein O-linked glycosylation via threonine. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for GALNT11. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = GALNT11 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of GALNT11, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr7:151,782,698–151,783,271 | 242.6 kb | Distal (>10kb) Multiome | 498 | |
| chr7:151,837,433–151,838,118 | 187.9 kb | Distal (>10kb) Multiome | 109 | |
| chr7:151,875,185–151,876,886 | 149.6 kb | Distal (>10kb) Multiome | 561 | |
| chr7:151,877,002–151,877,801 | 148.1 kb | Distal (>10kb) Multiome | 424 | |
| chr7:152,025,196–152,026,407 | 14 bp | At TSS Multiome | 795 | |
| chr7:152,030,166–152,030,386 | 4.5 kb | Proximal (<10kb) | 85 |
Genomic view of the GALNT11 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.