Enables RNA binding activity. Located in cytosol. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for FAM120A. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = FAM120A upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of FAM120A, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr9:93,159,802–93,160,270 | 291.8 kb | Distal (>10kb) Multiome | 500 | |
| chr9:93,183,782–93,185,608 | 267.7 kb | Distal (>10kb) Multiome | 401 | |
| chr9:93,346,091–93,346,711 | 105.6 kb | Distal (>10kb) Multiome | 137 | |
| chr9:93,364,969–93,366,461 | 86.1 kb | Distal (>10kb) Multiome | 123 | |
| chr9:93,450,848–93,452,597 | 277 bp | At TSS Multiome | 770 | |
| chr9:93,453,260–93,453,968 | 1.7 kb | Proximal (<10kb) Multiome | 535 | |
| chr9:93,566,407–93,567,185 | 114.8 kb | Distal (>10kb) Multiome | 816 |
Genomic view of the FAM120A locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.