Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ENTREP2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ENTREP2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ENTREP2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr15:29,345,363–29,346,382 | 225.1 kb | Distal (>10kb) Multiome | 124 | |
| chr15:29,568,912–29,569,063 | 921 bp | At TSS | 60 | |
| chr15:29,569,853–29,571,577 | 14 bp | At TSS Multiome | 290 | |
| chr15:29,572,157–29,572,375 | 2.2 kb | Proximal (<10kb) | 80 | |
| chr15:29,674,491–29,675,851 | 103.9 kb | Distal (>10kb) Multiome | 397 | |
| chr15:29,821,422–29,823,117 | 250.8 kb | Distal (>10kb) Multiome | 808 |
Genomic view of the ENTREP2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.