Predicted to enable inorganic anion transmembrane transporter activity and organic anion transmembrane transporter activity. Predicted to be involved in chloride transmembrane transport and sulfate transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ENSG00000293429. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ENSG00000293429 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ENSG00000293429, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr12:57,609,052–57,609,957 | 9.6 kb | Proximal (<10kb) | 83 | |
| chr12:57,610,841–57,611,876 | 7.7 kb | Proximal (<10kb) | 558 | |
| chr12:57,614,300–57,614,474 | 5.1 kb | Proximal (<10kb) | 101 | |
| chr12:57,619,368–57,619,897 | at TSS | At TSS | 197 | |
| chr12:57,621,603–57,622,199 | 2.1 kb | Proximal (<10kb) | 446 | |
| chr12:57,627,535–57,628,303 | 8.0 kb | Proximal (<10kb) | 115 |
Genomic view of the ENSG00000293429 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.