Predicted to be involved in flagellated sperm motility. Located in axonemal microtubule and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CFAP95. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CFAP95 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CFAP95, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr9:69,671,854–69,673,410 | 148.7 kb | Distal (>10kb) Multiome | 654 | |
| chr9:69,759,439–69,760,486 | 60.8 kb | Distal (>10kb) Multiome | 751 | |
| chr9:69,820,343–69,821,096 | 101 bp | At TSS Multiome | 239 | |
| chr9:69,823,108–69,824,042 | 2.8 kb | Proximal (<10kb) Multiome | 59 | |
| chr9:69,986,283–69,987,113 | 165.9 kb | Distal (>10kb) Multiome | 65 | |
| chr9:70,043,398–70,045,147 | 224.0 kb | Distal (>10kb) Multiome | 310 |
Genomic view of the CFAP95 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.