Involved in protein localization. Located in Golgi apparatus; microtubule cytoskeleton; and nuclear membrane. Part of centriolar subdistal appendage. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CEP128. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CEP128 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CEP128, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr14:78,985,556–78,986,174 | 1955.9 kb | Distal (>10kb) Multiome HiCAR | 171 | |
| chr14:79,091,225–79,091,881 | 1850.1 kb | Distal (>10kb) Multiome HiCAR | 174 | |
| chr14:80,584,221–80,585,126 | 357.0 kb | Distal (>10kb) Multiome | 158 | |
| chr14:80,941,041–80,942,411 | 48 bp | At TSS Multiome | 702 | |
| chr14:80,954,799–80,956,015 | 13.3 kb | Distal (>10kb) Multiome | 534 | |
| chr14:81,169,725–81,171,107 | 228.8 kb | Distal (>10kb) Multiome | 780 | |
| chr14:81,219,039–81,221,949 | 279.4 kb | Distal (>10kb) Multiome | 1204 |
Genomic view of the CEP128 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.