Located in centrosome; ciliary basal body; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CCDC81. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CCDC81 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CCDC81, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr11:86,151,187–86,151,901 | 223.2 kb | Distal (>10kb) Multiome | 356 | |
| chr11:86,172,744–86,173,502 | 201.7 kb | Distal (>10kb) Multiome | 240 | |
| chr11:86,244,135–86,246,099 | 129.7 kb | Distal (>10kb) Multiome | 959 | |
| chr11:86,302,015–86,302,729 | 72.5 kb | Distal (>10kb) Multiome | 873 | |
| chr11:86,374,442–86,374,974 | at TSS | At TSS | 124 | |
| chr11:86,421,815–86,422,714 | 47.5 kb | Distal (>10kb) Multiome | 141 | |
| chr11:86,422,902–86,424,146 | 49.0 kb | Distal (>10kb) Multiome | 152 | |
| chr11:86,513,467–86,514,411 | 139.2 kb | Distal (>10kb) Multiome | 148 | |
| chr11:86,571,370–86,571,978 | 197.0 kb | Distal (>10kb) Multiome | 310 |
Genomic view of the CCDC81 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.