Enables protein serine/threonine kinase binding activity. Involved in centriole-centriole cohesion. Located in centriole. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for CCDC102B. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CCDC102B upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CCDC102B, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr18:67,368,248–67,369,001 | 1346.6 kb | Distal (>10kb) Multiome HiCAR | 96 | |
| chr18:67,455,460–67,456,258 | 1259.3 kb | Distal (>10kb) Multiome HiCAR | 86 | |
| chr18:67,515,663–67,517,723 | 1199.3 kb | Distal (>10kb) Multiome HiCAR | 579 | |
| chr18:67,585,750–67,587,104 | 1128.9 kb | Distal (>10kb) Multiome HiCAR | 152 | |
| chr18:68,561,806–68,563,075 | 152.9 kb | Distal (>10kb) Multiome | 132 | |
| chr18:68,713,229–68,713,429 | 1.8 kb | Proximal (<10kb) | 43 | |
| chr18:68,714,344–68,715,550 | 129 bp | At TSS Multiome | 900 | |
| chr18:68,942,219–68,945,153 | 227.3 kb | Distal (>10kb) Multiome | 285 |
Genomic view of the CCDC102B locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.