Enables microtubule minus-end binding activity. Involved in several processes, including axon development; regulation of dendrite development; and regulation of organelle organization. Located in Golgi apparatus; cytosol; and microtubule cytoskeleton. [provided by Alliance of Genome Resources, Apr 2025]
Transcription factors with Perturb-seq knockdown data for CAMSAP2. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = CAMSAP2 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of CAMSAP2, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr1:200,620,328–200,621,096 | 118.1 kb | Distal (>10kb) Multiome | 739 | |
| chr1:200,669,293–200,670,631 | 69.0 kb | Distal (>10kb) Multiome | 1078 | |
| chr1:200,732,536–200,732,761 | 6.1 kb | Proximal (<10kb) | 73 | |
| chr1:200,738,299–200,740,095 | 105 bp | At TSS Multiome | 831 | |
| chr1:200,890,766–200,892,246 | 152.5 kb | Distal (>10kb) Multiome | 761 | |
| chr1:200,915,808–200,916,700 | 177.4 kb | Distal (>10kb) Multiome | 219 | |
| chr1:201,014,162–201,014,786 | 275.6 kb | Distal (>10kb) Multiome | 160 | |
| chr1:201,020,041–201,020,958 | 281.5 kb | Distal (>10kb) Multiome | 289 | |
| chr1:201,021,071–201,021,621 | 282.4 kb | Distal (>10kb) Multiome | 164 | |
| chr1:201,022,936–201,024,467 | 284.8 kb | Distal (>10kb) Multiome | 436 |
Genomic view of the CAMSAP2 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.