Enables identical protein binding activity. Predicted to be located in extracellular region and membrane. Predicted to be part of collagen trimer. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for C1QTNF6. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = C1QTNF6 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of C1QTNF6, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr22:37,018,841–37,020,143 | 179.8 kb | Distal (>10kb) Multiome | 684 | |
| chr22:37,051,550–37,052,220 | 147.6 kb | Distal (>10kb) Multiome | 351 | |
| chr22:37,186,352–37,186,517 | 1.8 kb | Proximal (<10kb) | 102 | |
| chr22:37,187,959–37,189,489 | 11.0 kb | Distal (>10kb) Multiome | 340 | |
| chr22:37,192,336–37,192,506 | 4.0 kb | Proximal (<10kb) | 18 | |
| chr22:37,198,530–37,200,140 | 147 bp | At TSS Multiome | 875 | |
| chr22:37,419,824–37,420,580 | 220.9 kb | Distal (>10kb) Multiome | 150 |
Genomic view of the C1QTNF6 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.