Enables acetylglucosaminyltransferase activity. Involved in keratan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for B3GNT7. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = B3GNT7 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of B3GNT7, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr2:231,189,962–231,191,188 | 205.0 kb | Distal (>10kb) Multiome | 358 | |
| chr2:231,198,151–231,199,150 | 197.0 kb | Distal (>10kb) Multiome | 760 | |
| chr2:231,297,093–231,297,547 | 98.4 kb | Distal (>10kb) Multiome HiCAR | 344 | |
| chr2:231,337,851–231,338,311 | 57.6 kb | Distal (>10kb) Multiome | 58 | |
| chr2:231,370,064–231,371,397 | 24.8 kb | Distal (>10kb) Multiome | 214 | |
| chr2:231,375,406–231,377,370 | 19.2 kb | Distal (>10kb) Multiome | 232 | |
| chr2:231,393,165–231,393,378 | 2.3 kb | Proximal (<10kb) | 89 | |
| chr2:231,394,766–231,396,655 | 19 bp | At TSS Multiome | 339 | |
| chr2:231,410,617–231,411,062 | 15.1 kb | Distal (>10kb) Multiome | 150 | |
| chr2:231,411,845–231,413,014 | 16.7 kb | Distal (>10kb) Multiome | 691 | |
| chr2:231,463,695–231,465,687 | 68.9 kb | Distal (>10kb) Multiome | 1126 | |
| chr2:231,482,645–231,483,215 | 87.3 kb | Distal (>10kb) Multiome | 450 | |
| chr2:231,483,468–231,484,163 | 88.2 kb | Distal (>10kb) Multiome | 197 | |
| chr2:231,514,074–231,514,984 | 118.8 kb | Distal (>10kb) Multiome | 731 | |
| chr2:231,530,197–231,530,963 | 134.8 kb | Distal (>10kb) Multiome | 395 | |
| chr2:231,557,621–231,558,377 | 162.4 kb | Distal (>10kb) Multiome | 215 | |
| chr2:231,601,487–231,602,111 | 206.1 kb | Distal (>10kb) Multiome | 239 | |
| chr2:231,604,056–231,605,408 | 209.1 kb | Distal (>10kb) Multiome | 677 | |
| chr2:231,611,822–231,613,019 | 217.0 kb | Distal (>10kb) Multiome | 673 | |
| chr2:231,613,128–231,615,041 | 218.5 kb | Distal (>10kb) Multiome | 956 | |
| chr2:231,621,037–231,621,485 | 225.8 kb | Distal (>10kb) Multiome | 189 | |
| chr2:231,661,829–231,663,079 | 266.7 kb | Distal (>10kb) Multiome | 645 | |
| chr2:231,666,093–231,667,175 | 270.9 kb | Distal (>10kb) Multiome | 778 | |
| chr2:231,672,732–231,673,910 | 277.7 kb | Distal (>10kb) Multiome | 570 | |
| chr2:231,674,697–231,675,325 | 279.4 kb | Distal (>10kb) Multiome | 455 | |
| chr2:231,679,801–231,681,869 | 285.5 kb | Distal (>10kb) Multiome | 959 | |
| chr2:231,687,250–231,687,863 | 291.8 kb | Distal (>10kb) Multiome | 640 |
Genomic view of the B3GNT7 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.