DE-6

DE-6.13

Submodule 12 genes

Histone and nucleosome chromatin organization

This 12-gene module includes histone variants H1-2, H1-4, H2AC20, H1-3, and H1-5, with enrichment for nucleosome structure, protein-DNA complexes, and chromatin organization. The module is associated with structural chromatin functions including epigenetic regulation of gene expression, chromatin remodeling, and structural molecule activity. No transcription factor knockdown data are available for this module.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (12)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z