RNA-seq expression profiles of SOX17 and CXCR4 across the ESC → Definitive Endoderm time course, showing whether the TF and its putative target are co-expressed.
Distribution of per-gene regression coefficients for each SOX17 guide RNA in the Perturb-seq DE screen. The marker shows where CXCR4 falls in each distribution, indicating the direction and magnitude of its response to SOX17 knockdown.
Regulatory elements (ATAC-seq peaks) linking SOX17 to CXCR4, supported by TOBIAS motif footprints and/or ChIP-seq peak overlap. The diagram connects each binding source through intermediate elements to the target gene — click any pill to filter the view.
Genomic view centered on regulatory elements linking SOX17 to CXCR4. Tracks include TF binding peaks (motif footprints and ChIP-seq), ATAC-seq accessibility, RNA-seq expression, and arc-loop connections from each element to the CXCR4 TSS — all across the ESC → DE time course.