Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZNF267. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF267 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF267, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr16:30,984,837–30,985,709 | 888.6 kb | Distal (>10kb) Multiome HiCAR | 787 | |
| chr16:31,700,204–31,701,065 | 173.2 kb | Distal (>10kb) Multiome | 787 | |
| chr16:31,712,839–31,714,180 | 160.5 kb | Distal (>10kb) Multiome | 930 | |
| chr16:31,868,693–31,868,903 | 4.9 kb | Proximal (<10kb) | 134 | |
| chr16:31,873,239–31,874,541 | 35 bp | At TSS Multiome | 714 |
Genomic view of the ZNF267 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.