Enables RNA binding activity. Predicted to be involved in insulin receptor signaling pathway. Predicted to be located in nuclear speck and nucleolus. Predicted to be active in cytosol and membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZNF106. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF106 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF106, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr15:42,273,010–42,273,873 | 217.7 kb | Distal (>10kb) Multiome | 883 | |
| chr15:42,457,473–42,457,710 | at TSS | At TSS | 122 | |
| chr15:42,490,811–42,491,337 | 11 bp | At TSS Multiome | 807 | |
| chr15:42,495,454–42,495,753 | 4.3 kb | Proximal (<10kb) | 581 | |
| chr15:42,548,416–42,549,113 | 57.6 kb | Distal (>10kb) Multiome | 848 | |
| chr15:42,575,082–42,575,846 | 84.3 kb | Distal (>10kb) Multiome | 785 | |
| chr15:42,736,813–42,737,498 | 246.1 kb | Distal (>10kb) Multiome | 576 |
Genomic view of the ZNF106 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.