Predicted to enable zinc ion binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZFP62. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZFP62 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZFP62, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr5:180,618,726–180,619,463 | 242.1 kb | Distal (>10kb) Multiome | 289 | |
| chr5:180,648,868–180,649,861 | 212.1 kb | Distal (>10kb) Multiome | 281 | |
| chr5:180,802,126–180,804,080 | 58.4 kb | Distal (>10kb) Multiome HiCAR | 796 | |
| chr5:180,809,580–180,811,300 | 51.0 kb | Distal (>10kb) Multiome HiCAR | 1018 | |
| chr5:180,831,123–180,831,970 | 29.7 kb | Distal (>10kb) Multiome | 549 | |
| chr5:180,860,430–180,861,900 | 660 bp | At TSS Multiome | 974 | |
| chr5:181,027,794–181,028,639 | 166.9 kb | Distal (>10kb) Multiome | 337 | |
| chr5:181,069,860–181,070,513 | 208.9 kb | Distal (>10kb) Multiome | 136 |
Genomic view of the ZFP62 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.